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Interactions of antiretroviral drugs with the SLC22A1 (OCT1) drug transporter

The SLC22A1 influx transporter is expressed on the basolateral membrane of hepatocytes and is involved in the excretion of numerous cations. Inhibition of SLC22A1 by several antiretrovirals, such as the protease inhibitor darunavir, has not previously been determined. In order to better understand a...

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Detalles Bibliográficos
Autores principales:	Moss, Darren M., Liptrott, Neill J., Siccardi, Marco, Owen, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392609/ https://www.ncbi.nlm.nih.gov/pubmed/25914645 http://dx.doi.org/10.3389/fphar.2015.00078

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