Altered balance of interleukin-13/interferon-gamma contributes to lacrimal gland destruction and secretory dysfunction in CD25 knockout model of Sjögren’s syndrome

INTRODUCTION: The lacrimal gland (LG) of the CD25(-)/(-) model of Sjögren’s syndrome (SS) has high interleukin (IL)-17, IL-13 and interferon-gamma (IFN-γ) cytokines. The specific contribution of these cytokines to the onset and severity of dacryoadenitis in the CD25(-)/(-) mice has not been evaluate...

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Detalles Bibliográficos
Autores principales: Bian, Fang, Barbosa, Flavia L, Corrales, Rosa M, Pelegrino, Flavia SA, Volpe, Eugene A, Pflugfelder, Stephen C, de Paiva, Cintia S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392623/
https://www.ncbi.nlm.nih.gov/pubmed/25889094
http://dx.doi.org/10.1186/s13075-015-0582-9

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