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Inhibitory activities of short linear motifs underlie Hox interactome specificity in vivo

Hox proteins are well-established developmental regulators that coordinate cell fate and morphogenesis throughout embryogenesis. In contrast, our knowledge of their specific molecular modes of action is limited to the interaction with few cofactors. Here, we show that Hox proteins are able to intera...

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Detalles Bibliográficos
Autores principales: Baëza, Manon, Viala, Séverine, Heim, Marjorie, Dard, Amélie, Hudry, Bruno, Duffraisse, Marilyne, Rogulja-Ortmann, Ana, Brun, Christine, Merabet, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392834/
https://www.ncbi.nlm.nih.gov/pubmed/25869471
http://dx.doi.org/10.7554/eLife.06034