Constrained Peptides as Miniature Protein Structures

This paper discusses the recent developments of protein engineering using both covalent and noncovalent bonds to constrain peptides, forcing them into designed protein secondary structures. These constrained peptides subsequently can be used as peptidomimetics for biological functions such as regula...

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Detalles Bibliográficos
Autor principal: Yin, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392992/
https://www.ncbi.nlm.nih.gov/pubmed/25969758
http://dx.doi.org/10.5402/2012/692190
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author Yin, Hang
author_facet Yin, Hang
author_sort Yin, Hang
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description This paper discusses the recent developments of protein engineering using both covalent and noncovalent bonds to constrain peptides, forcing them into designed protein secondary structures. These constrained peptides subsequently can be used as peptidomimetics for biological functions such as regulations of protein-protein interactions.
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spelling pubmed-43929922015-05-12 Constrained Peptides as Miniature Protein Structures Yin, Hang ISRN Biochem Review Article This paper discusses the recent developments of protein engineering using both covalent and noncovalent bonds to constrain peptides, forcing them into designed protein secondary structures. These constrained peptides subsequently can be used as peptidomimetics for biological functions such as regulations of protein-protein interactions. International Scholarly Research Network 2012-09-26 /pmc/articles/PMC4392992/ /pubmed/25969758 http://dx.doi.org/10.5402/2012/692190 Text en Copyright © 2012 Hang Yin. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Yin, Hang
Constrained Peptides as Miniature Protein Structures
title Constrained Peptides as Miniature Protein Structures
title_full Constrained Peptides as Miniature Protein Structures
title_fullStr Constrained Peptides as Miniature Protein Structures
title_full_unstemmed Constrained Peptides as Miniature Protein Structures
title_short Constrained Peptides as Miniature Protein Structures
title_sort constrained peptides as miniature protein structures
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392992/
https://www.ncbi.nlm.nih.gov/pubmed/25969758
http://dx.doi.org/10.5402/2012/692190
work_keys_str_mv AT yinhang constrainedpeptidesasminiatureproteinstructures

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