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α-Actinin-4 Enhances Colorectal Cancer Cell Invasion by Suppressing Focal Adhesion Maturation

α-Actinins (ACTNs) are known to crosslink actin filaments at focal adhesions in migrating cells. Among the four isoforms of mammalian ACTNs, ACTN1 and ACTN4 are ubiquitously expressed. Recently, ACTN4 was reported to enhance cancer cell motility, invasion, and metastasis. However, the mechanism by w...

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Detalles Bibliográficos
Autores principales:	Fukumoto, Miki, Kurisu, Shusaku, Yamada, Tesshi, Takenawa, Tadaomi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393021/ https://www.ncbi.nlm.nih.gov/pubmed/25860875 http://dx.doi.org/10.1371/journal.pone.0120616

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