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Effect of acute acid-base disturbances on the phosphorylation of phospholipase C-γ1 and Erk1/2 in the renal proximal tubule

The renal proximal tubule (PT) plays a major role in whole-body pH homeostasis by secreting H(+) into the tubule lumen. Previous work demonstrated that PTs respond to basolateral changes in [CO(2)] and [[Image: see text]] by appropriately altering H(+) secretion—responses blocked by the ErbB inhibit...

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Detalles Bibliográficos
Autores principales:	Skelton, Lara A, Boron, Walter F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393148/ https://www.ncbi.nlm.nih.gov/pubmed/25780091 http://dx.doi.org/10.14814/phy2.12280

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