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Changes in myoplasmic Ca(2+) during fatigue differ between FDB fibers, between glibenclamide-exposed and Kir6.2(-/-) fibers and are further modulated by verapamil
One objective of this study was to document how individual FDB muscle fibers depend on the myoprotection of KATP channels during fatigue. Verapamil, a CaV1.1 channel blocker, prevents large increases in unstimulated force during fatigue in KATP-channel-deficient muscles. A second objective was to de...
Autores principales: | Selvin, David, Renaud, Jean-Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393149/ https://www.ncbi.nlm.nih.gov/pubmed/25742954 http://dx.doi.org/10.14814/phy2.12303 |
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