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Changes in myoplasmic Ca(2+) during fatigue differ between FDB fibers, between glibenclamide-exposed and Kir6.2(-/-) fibers and are further modulated by verapamil

One objective of this study was to document how individual FDB muscle fibers depend on the myoprotection of KATP channels during fatigue. Verapamil, a CaV1.1 channel blocker, prevents large increases in unstimulated force during fatigue in KATP-channel-deficient muscles. A second objective was to de...

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Detalles Bibliográficos
Autores principales: Selvin, David, Renaud, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393149/
https://www.ncbi.nlm.nih.gov/pubmed/25742954
http://dx.doi.org/10.14814/phy2.12303

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