Disturbed shear stress reduces Klf2 expression in arterial-venous fistulae in vivo

Laminar shear stress (SS) induces an antiproliferative and anti-inflammatory endothelial phenotype and increases Klf2 expression. We altered the diameter of an arteriovenous fistula (AVF) in the mouse model to determine whether increased fistula diameter produces disturbed SS in vivo and if acutely...

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Detalles Bibliográficos
Autores principales: Yamamoto, Kota, Protack, Clinton D, Kuwahara, Go, Tsuneki, Masayuki, Hashimoto, Takuya, Hall, Michael R, Assi, Roland, Brownson, Kirstyn E, Foster, Trenton R, Bai, Hualong, Wang, Mo, Madri, Joseph A, Dardik, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393175/
https://www.ncbi.nlm.nih.gov/pubmed/25780089
http://dx.doi.org/10.14814/phy2.12348

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