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Neurovascular control following small muscle-mass exercise in humans
Sustained postexercise vasodilation, which may be mediated at both a neural and vascular level, is seen in previously active skeletal muscle vascular beds following both large and small muscle-mass exercise. Blunted sympathetic vascular transduction and a downward resetting of the arterial barorefle...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393198/ https://www.ncbi.nlm.nih.gov/pubmed/25649250 http://dx.doi.org/10.14814/phy2.12289 |
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author | Buck, Tahisha M Romero, Steven A Ely, Matthew R Sieck, Dylan C Abdala, Pedro M Halliwill, John R |
author_facet | Buck, Tahisha M Romero, Steven A Ely, Matthew R Sieck, Dylan C Abdala, Pedro M Halliwill, John R |
author_sort | Buck, Tahisha M |
collection | PubMed |
description | Sustained postexercise vasodilation, which may be mediated at both a neural and vascular level, is seen in previously active skeletal muscle vascular beds following both large and small muscle-mass exercise. Blunted sympathetic vascular transduction and a downward resetting of the arterial baroreflex contribute to this vasodilation after cycling (large muscle-mass exercise), but it is unknown if these responses also contribute to sustained vasodilation following small muscle-mass exercise. This study aimed to determine if baroreflex sensitivity is altered, the baroreflex is reset, or if sympathetic vascular transduction is blunted following small muscle-mass exercise. Eleven healthy, college-aged subjects (five males, six females) completed one-leg dynamic knee-extension exercise for 1 h at 60% of peak power output. While cardiovagal baroreflex sensitivity was increased ∼23% postexercise relative to preexercise (P < 0.05), vascular and integrated baroreflex sensitivity were not altered following exercise (P = 0.31 and P = 0.48). The baroreflex did not exhibit resetting (P > 0.69), and there was no evidence of changes in vascular transduction following exercise (P = 0.73). In conclusion, and in contrast to large muscle-mass exercise, it appears that small muscle-mass exercise produces a sustained postexercise vasodilation that is largely independent of central changes in the baroreflex. |
format | Online Article Text |
id | pubmed-4393198 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BlackWell Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-43931982015-04-20 Neurovascular control following small muscle-mass exercise in humans Buck, Tahisha M Romero, Steven A Ely, Matthew R Sieck, Dylan C Abdala, Pedro M Halliwill, John R Physiol Rep Original Research Sustained postexercise vasodilation, which may be mediated at both a neural and vascular level, is seen in previously active skeletal muscle vascular beds following both large and small muscle-mass exercise. Blunted sympathetic vascular transduction and a downward resetting of the arterial baroreflex contribute to this vasodilation after cycling (large muscle-mass exercise), but it is unknown if these responses also contribute to sustained vasodilation following small muscle-mass exercise. This study aimed to determine if baroreflex sensitivity is altered, the baroreflex is reset, or if sympathetic vascular transduction is blunted following small muscle-mass exercise. Eleven healthy, college-aged subjects (five males, six females) completed one-leg dynamic knee-extension exercise for 1 h at 60% of peak power output. While cardiovagal baroreflex sensitivity was increased ∼23% postexercise relative to preexercise (P < 0.05), vascular and integrated baroreflex sensitivity were not altered following exercise (P = 0.31 and P = 0.48). The baroreflex did not exhibit resetting (P > 0.69), and there was no evidence of changes in vascular transduction following exercise (P = 0.73). In conclusion, and in contrast to large muscle-mass exercise, it appears that small muscle-mass exercise produces a sustained postexercise vasodilation that is largely independent of central changes in the baroreflex. BlackWell Publishing Ltd 2015-02-04 /pmc/articles/PMC4393198/ /pubmed/25649250 http://dx.doi.org/10.14814/phy2.12289 Text en © 2015 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Buck, Tahisha M Romero, Steven A Ely, Matthew R Sieck, Dylan C Abdala, Pedro M Halliwill, John R Neurovascular control following small muscle-mass exercise in humans |
title | Neurovascular control following small muscle-mass exercise in humans |
title_full | Neurovascular control following small muscle-mass exercise in humans |
title_fullStr | Neurovascular control following small muscle-mass exercise in humans |
title_full_unstemmed | Neurovascular control following small muscle-mass exercise in humans |
title_short | Neurovascular control following small muscle-mass exercise in humans |
title_sort | neurovascular control following small muscle-mass exercise in humans |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393198/ https://www.ncbi.nlm.nih.gov/pubmed/25649250 http://dx.doi.org/10.14814/phy2.12289 |
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