Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass-Spectrometry (MALDI-TOF MS) Based Typing of Extended-Spectrum β-Lactamase Producing E. coli – A Novel Tool for Real-Time Outbreak Investigation

Epidemiologically linked clusters are confirmed by typing strains with molecular typing such as pulsed-field gel electrophoresis (PFGE). We compared six extended-spectrum β-lactamase producing E. coli of a PFGE-related cluster with Matrix-assisted laser desorption/ionization-time of flight mass-spec...

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Detalles Bibliográficos
Autores principales: Egli, Adrian, Tschudin-Sutter, Sarah, Oberle, Michael, Goldenberger, Daniel, Frei, Reno, Widmer, Andreas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393243/
https://www.ncbi.nlm.nih.gov/pubmed/25860943
http://dx.doi.org/10.1371/journal.pone.0120624
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author Egli, Adrian
Tschudin-Sutter, Sarah
Oberle, Michael
Goldenberger, Daniel
Frei, Reno
Widmer, Andreas F.
author_facet Egli, Adrian
Tschudin-Sutter, Sarah
Oberle, Michael
Goldenberger, Daniel
Frei, Reno
Widmer, Andreas F.
author_sort Egli, Adrian
collection PubMed
description Epidemiologically linked clusters are confirmed by typing strains with molecular typing such as pulsed-field gel electrophoresis (PFGE). We compared six extended-spectrum β-lactamase producing E. coli of a PFGE-related cluster with Matrix-assisted laser desorption/ionization-time of flight mass-spectrometry based typing that confirmed relatedness faster and more cost-effective, but as reliable as PFGE.
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spelling pubmed-43932432015-04-21 Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass-Spectrometry (MALDI-TOF MS) Based Typing of Extended-Spectrum β-Lactamase Producing E. coli – A Novel Tool for Real-Time Outbreak Investigation Egli, Adrian Tschudin-Sutter, Sarah Oberle, Michael Goldenberger, Daniel Frei, Reno Widmer, Andreas F. PLoS One Research Article Epidemiologically linked clusters are confirmed by typing strains with molecular typing such as pulsed-field gel electrophoresis (PFGE). We compared six extended-spectrum β-lactamase producing E. coli of a PFGE-related cluster with Matrix-assisted laser desorption/ionization-time of flight mass-spectrometry based typing that confirmed relatedness faster and more cost-effective, but as reliable as PFGE. Public Library of Science 2015-04-10 /pmc/articles/PMC4393243/ /pubmed/25860943 http://dx.doi.org/10.1371/journal.pone.0120624 Text en © 2015 Egli et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Egli, Adrian
Tschudin-Sutter, Sarah
Oberle, Michael
Goldenberger, Daniel
Frei, Reno
Widmer, Andreas F.
Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass-Spectrometry (MALDI-TOF MS) Based Typing of Extended-Spectrum β-Lactamase Producing E. coli – A Novel Tool for Real-Time Outbreak Investigation
title Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass-Spectrometry (MALDI-TOF MS) Based Typing of Extended-Spectrum β-Lactamase Producing E. coli – A Novel Tool for Real-Time Outbreak Investigation
title_full Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass-Spectrometry (MALDI-TOF MS) Based Typing of Extended-Spectrum β-Lactamase Producing E. coli – A Novel Tool for Real-Time Outbreak Investigation
title_fullStr Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass-Spectrometry (MALDI-TOF MS) Based Typing of Extended-Spectrum β-Lactamase Producing E. coli – A Novel Tool for Real-Time Outbreak Investigation
title_full_unstemmed Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass-Spectrometry (MALDI-TOF MS) Based Typing of Extended-Spectrum β-Lactamase Producing E. coli – A Novel Tool for Real-Time Outbreak Investigation
title_short Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass-Spectrometry (MALDI-TOF MS) Based Typing of Extended-Spectrum β-Lactamase Producing E. coli – A Novel Tool for Real-Time Outbreak Investigation
title_sort matrix-assisted laser desorption/ionization time of flight mass-spectrometry (maldi-tof ms) based typing of extended-spectrum β-lactamase producing e. coli – a novel tool for real-time outbreak investigation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393243/
https://www.ncbi.nlm.nih.gov/pubmed/25860943
http://dx.doi.org/10.1371/journal.pone.0120624
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