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Tracheal Dysplasia Precedes Bronchial Dysplasia in Mouse Model of N-Nitroso Trischloroethylurea Induced Squamous Cell Lung Cancer
Squamous cell lung cancer (SCC) is the second leading cause of lung cancer death in the US and has a 5-year survival rate of only 16%. Histological changes in the bronchial epithelium termed dysplasia are precursors to invasive SCC. However, the cellular mechanisms that cause dysplasia are unknown....
Autores principales: | Ghosh, Moumita, Dwyer-Nield, Lori D., Kwon, Jennifer B., Barthel, Lea, Janssen, William J., Merrick, Daniel T., Keith, Robert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393296/ https://www.ncbi.nlm.nih.gov/pubmed/25860262 http://dx.doi.org/10.1371/journal.pone.0122823 |
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