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Biochemical Analysis of the NAD(+)-Dependent Malate Dehydrogenase, a Substrate of Several Serine/Threonine Protein Kinases of Mycobacterium tuberculosis

PknD is one of the eleven eukaryotic-like serine/threonine protein kinases (STPKs) of Mycobacterium tuberculosis (Mtb). In vitro phosphorylation assays with the active recombinant PknD showed that the intracellular protein NAD(+)-dependent malate dehydrogenase (MDH) is a substrate of this kinase. MD...

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Detalles Bibliográficos
Autores principales: Wang, Xiao Ming, Soetaert, Karine, Peirs, Priska, Kalai, Michaël, Fontaine, Véronique, Dehaye, Jean Paul, Lefèvre, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393303/
https://www.ncbi.nlm.nih.gov/pubmed/25860441
http://dx.doi.org/10.1371/journal.pone.0123327