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The GTPase-Activating Protein Rga1 Interacts with Rho3 GTPase and May Regulate Its Function in Polarized Growth in Budding Yeast

In budding yeast, Rga1 negatively regulates the Rho GTPase Cdc42 by acting as a GTPase-activating protein (GAP) for Cdc42. To gain insight into the function and regulation of Rga1, we overexpressed Rga1 and an N-terminally truncated Rga1-C538 (a.a. 538-1007) segment. Overexpression of Rga1-C538 but...

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Detalles Bibliográficos
Autores principales: He, Fei, Nie, Wen-Chao, Tong, Zongtian, Yuan, Si-Min, Gong, Ting, Liao, Yuan, Bi, Erfei, Gao, Xiang-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393305/
https://www.ncbi.nlm.nih.gov/pubmed/25860339
http://dx.doi.org/10.1371/journal.pone.0123326

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