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The GTPase-Activating Protein Rga1 Interacts with Rho3 GTPase and May Regulate Its Function in Polarized Growth in Budding Yeast
In budding yeast, Rga1 negatively regulates the Rho GTPase Cdc42 by acting as a GTPase-activating protein (GAP) for Cdc42. To gain insight into the function and regulation of Rga1, we overexpressed Rga1 and an N-terminally truncated Rga1-C538 (a.a. 538-1007) segment. Overexpression of Rga1-C538 but...
Autores principales: | He, Fei, Nie, Wen-Chao, Tong, Zongtian, Yuan, Si-Min, Gong, Ting, Liao, Yuan, Bi, Erfei, Gao, Xiang-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393305/ https://www.ncbi.nlm.nih.gov/pubmed/25860339 http://dx.doi.org/10.1371/journal.pone.0123326 |
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