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The natural product brartemicin is a high affinity ligand for the carbohydrate-recognition domain of the macrophage receptor mincle

We demonstrate that the natural product brartemicin, a newly discovered inhibitor of cancer cell invasion, is a high-affinity ligand of the carbohydrate-recognition domain (CRD) of the C-type lectin mincle. Recent studies have revealed that mincle is a key macrophage receptor for the mycobacterial v...

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Detalles Bibliográficos
Autores principales:	Jacobsen, Kristian M., Keiding, Ulrik B., Clement, Lise L., Schaffert, Eva S., Rambaruth, Neela D. S., Johannsen, Mogens, Drickamer, Kurt, Poulsen, Thomas B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2015
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393326/ https://www.ncbi.nlm.nih.gov/pubmed/25893085 http://dx.doi.org/10.1039/c4md00512k

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