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Cardiomyocyte Ca(2+) handling and structure is regulated by degree and duration of mechanical load variation

Cardiac transverse (t)-tubules are altered during disease and may be regulated by stretch-sensitive molecules. The relationship between variations in the degree and duration of load and t-tubule structure remains unknown, as well as its implications for local Ca(2+)-induced Ca(2+) release (CICR). Ra...

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Detalles Bibliográficos
Autores principales: Ibrahim, Michael, Kukadia, Punam, Siedlecka, Urszula, Cartledge, James E, Navaratnarajah, Manoraj, Tokar, Sergiy, Van Doorn, Carin, Tsang, Victor T, Gorelik, Julia, Yacoub, Magdi H, Terracciano, Cesare M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393719/
https://www.ncbi.nlm.nih.gov/pubmed/22862818
http://dx.doi.org/10.1111/j.1582-4934.2012.01611.x