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BDNF-mediated migration of cardiac microvascular endothelial cells is impaired during ageing

This study indicates that brain-derived neurotrophic factor (BDNF) can promote young cardiac microvascular endothelial cells (CMECs) to migrate via the activation of the BDNF-TrkB-FL-PI3K/Akt pathway, which may benefit angiogenesis after myocardial infarction (MI). However, the ageing of CMECs led t...

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Detalles Bibliográficos
Autores principales:	Cao, Liang, Zhang, Liang, Chen, Siyun, Yuan, Ziqiang, Liu, Shaokun, Shen, Xiaotao, Zheng, Xin, Qi, Xufeng, Lee, Kenneth KH, Chan, John Yeuk-Hon, Cai, Dongqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393738/ https://www.ncbi.nlm.nih.gov/pubmed/22925160 http://dx.doi.org/10.1111/j.1582-4934.2012.01621.x

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