Hyper-reactive Malarial Splenomegaly (HMS) in a patient with β thalassaemia syndrome

This report describes a case of hyper-reactive malarial splenomegaly in a patient with a thalassaemia syndrome. Increased haemoglobin A(2) is valuable for the diagnosis of common forms of β-thalassemia, while haemoglobin F (HbF) helps in diagnosis of the rarer δβ- forms. Thalassemia is characterised...

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Detalles Bibliográficos
Autores principales: Amoako, Yaw Ampem, Bedu-Addo, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394002/
https://www.ncbi.nlm.nih.gov/pubmed/25883737
http://dx.doi.org/10.11604/pamj.2014.19.310.5576
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author Amoako, Yaw Ampem
Bedu-Addo, George
author_facet Amoako, Yaw Ampem
Bedu-Addo, George
author_sort Amoako, Yaw Ampem
collection PubMed
description This report describes a case of hyper-reactive malarial splenomegaly in a patient with a thalassaemia syndrome. Increased haemoglobin A(2) is valuable for the diagnosis of common forms of β-thalassemia, while haemoglobin F (HbF) helps in diagnosis of the rarer δβ- forms. Thalassemia is characterised by splenomegaly and is common in malaria endemic areas. Hyper-reactive malarial splenomegaly is also a common cause of massive splenomegaly in malaria endemic areas. Splenic enlargement regresses with prolonged antimalarial therapy
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spelling pubmed-43940022015-04-16 Hyper-reactive Malarial Splenomegaly (HMS) in a patient with β thalassaemia syndrome Amoako, Yaw Ampem Bedu-Addo, George Pan Afr Med J Case Report This report describes a case of hyper-reactive malarial splenomegaly in a patient with a thalassaemia syndrome. Increased haemoglobin A(2) is valuable for the diagnosis of common forms of β-thalassemia, while haemoglobin F (HbF) helps in diagnosis of the rarer δβ- forms. Thalassemia is characterised by splenomegaly and is common in malaria endemic areas. Hyper-reactive malarial splenomegaly is also a common cause of massive splenomegaly in malaria endemic areas. Splenic enlargement regresses with prolonged antimalarial therapy The African Field Epidemiology Network 2014-11-21 /pmc/articles/PMC4394002/ /pubmed/25883737 http://dx.doi.org/10.11604/pamj.2014.19.310.5576 Text en © Yaw Ampem Amoako et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Amoako, Yaw Ampem
Bedu-Addo, George
Hyper-reactive Malarial Splenomegaly (HMS) in a patient with β thalassaemia syndrome
title Hyper-reactive Malarial Splenomegaly (HMS) in a patient with β thalassaemia syndrome
title_full Hyper-reactive Malarial Splenomegaly (HMS) in a patient with β thalassaemia syndrome
title_fullStr Hyper-reactive Malarial Splenomegaly (HMS) in a patient with β thalassaemia syndrome
title_full_unstemmed Hyper-reactive Malarial Splenomegaly (HMS) in a patient with β thalassaemia syndrome
title_short Hyper-reactive Malarial Splenomegaly (HMS) in a patient with β thalassaemia syndrome
title_sort hyper-reactive malarial splenomegaly (hms) in a patient with β thalassaemia syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394002/
https://www.ncbi.nlm.nih.gov/pubmed/25883737
http://dx.doi.org/10.11604/pamj.2014.19.310.5576
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AT beduaddogeorge hyperreactivemalarialsplenomegalyhmsinapatientwithbthalassaemiasyndrome

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