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Coronary artery bypass grafting in the octogenarians: should we intervene, or leave them be?

OBJECTIVE: Coronary artery bypass grafting (CABG) is gradually increasing in the elderly population. We aimed to investigate the risk factors and the results of CABG along with the long term survival in patients at an age of 80 and older. METHODS: Between January 2002 and December 2011, a total of 1...

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Autores principales: Ozen, Anil, Unal, Ertekin Utku, Songur, Murat, Kocabeyoglu, Sinan Sabit, Hanedan, Onur, Yilmaz, Metin, Turkcan, Basak Soran, Cicekcioglu, Ferit, Kaplan, Sadi, Birincioglu, Cemal Levent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394330/
https://www.ncbi.nlm.nih.gov/pubmed/25870618
http://dx.doi.org/10.11909/j.issn.1671-5411.2015.02.005
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author Ozen, Anil
Unal, Ertekin Utku
Songur, Murat
Kocabeyoglu, Sinan Sabit
Hanedan, Onur
Yilmaz, Metin
Turkcan, Basak Soran
Cicekcioglu, Ferit
Kaplan, Sadi
Birincioglu, Cemal Levent
author_facet Ozen, Anil
Unal, Ertekin Utku
Songur, Murat
Kocabeyoglu, Sinan Sabit
Hanedan, Onur
Yilmaz, Metin
Turkcan, Basak Soran
Cicekcioglu, Ferit
Kaplan, Sadi
Birincioglu, Cemal Levent
author_sort Ozen, Anil
collection PubMed
description OBJECTIVE: Coronary artery bypass grafting (CABG) is gradually increasing in the elderly population. We aimed to investigate the risk factors and the results of CABG along with the long term survival in patients at an age of 80 and older. METHODS: Between January 2002 and December 2011, a total of 101 consecutive patients at an age of 80 and older who underwent CABG in our hospital were included in the study. The patients were followed and the long-term survival was estimated. RESULTS: The mean age of the patients was 82.98 ± 2.27 years. Sixty-four (63.4%) were males and 37 (36.6%) were females. Emergency surgery, duration of cardiopulmonary bypass, the intensive care unit (ICU) stay, inotropic support, intra aortic balloon pulsation application, amount of erythrocyte transfusion and fresh frozen plasma transfusion and ventilation period were significantly higher in the patients who died in the hospital. The duration of cardiopulmonary bypass (CPB) was found to be an independent predictor of mortality (OR: 1.18, 95% CI 1.01−1.38, P = 0.034). The in-hospital mortality was 16.8%. Kaplan-Meier analyses revealed a survival ratio of 91.3% at one year, 82.9% at three years and 69.0% at five years. CONCLUSIONS: Patients at the age of 80 and older can be candidates for the CABG procedure bearing in mind that they may have a longer ventilation period and intensive care unit stay. The morbidity and mortality of this age group is considered within an acceptable range. Approaches to minimize CPB, or the choice of off-pump surgery, may be a preventive method to lower the incidence of mortality. Hence, CABG may be performed in this age group with a satisfactory survival ratio.
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spelling pubmed-43943302015-04-13 Coronary artery bypass grafting in the octogenarians: should we intervene, or leave them be? Ozen, Anil Unal, Ertekin Utku Songur, Murat Kocabeyoglu, Sinan Sabit Hanedan, Onur Yilmaz, Metin Turkcan, Basak Soran Cicekcioglu, Ferit Kaplan, Sadi Birincioglu, Cemal Levent J Geriatr Cardiol Research Article OBJECTIVE: Coronary artery bypass grafting (CABG) is gradually increasing in the elderly population. We aimed to investigate the risk factors and the results of CABG along with the long term survival in patients at an age of 80 and older. METHODS: Between January 2002 and December 2011, a total of 101 consecutive patients at an age of 80 and older who underwent CABG in our hospital were included in the study. The patients were followed and the long-term survival was estimated. RESULTS: The mean age of the patients was 82.98 ± 2.27 years. Sixty-four (63.4%) were males and 37 (36.6%) were females. Emergency surgery, duration of cardiopulmonary bypass, the intensive care unit (ICU) stay, inotropic support, intra aortic balloon pulsation application, amount of erythrocyte transfusion and fresh frozen plasma transfusion and ventilation period were significantly higher in the patients who died in the hospital. The duration of cardiopulmonary bypass (CPB) was found to be an independent predictor of mortality (OR: 1.18, 95% CI 1.01−1.38, P = 0.034). The in-hospital mortality was 16.8%. Kaplan-Meier analyses revealed a survival ratio of 91.3% at one year, 82.9% at three years and 69.0% at five years. CONCLUSIONS: Patients at the age of 80 and older can be candidates for the CABG procedure bearing in mind that they may have a longer ventilation period and intensive care unit stay. The morbidity and mortality of this age group is considered within an acceptable range. Approaches to minimize CPB, or the choice of off-pump surgery, may be a preventive method to lower the incidence of mortality. Hence, CABG may be performed in this age group with a satisfactory survival ratio. Science Press 2015-03 /pmc/articles/PMC4394330/ /pubmed/25870618 http://dx.doi.org/10.11909/j.issn.1671-5411.2015.02.005 Text en Institute of Geriatric Cardiology http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.
spellingShingle Research Article
Ozen, Anil
Unal, Ertekin Utku
Songur, Murat
Kocabeyoglu, Sinan Sabit
Hanedan, Onur
Yilmaz, Metin
Turkcan, Basak Soran
Cicekcioglu, Ferit
Kaplan, Sadi
Birincioglu, Cemal Levent
Coronary artery bypass grafting in the octogenarians: should we intervene, or leave them be?
title Coronary artery bypass grafting in the octogenarians: should we intervene, or leave them be?
title_full Coronary artery bypass grafting in the octogenarians: should we intervene, or leave them be?
title_fullStr Coronary artery bypass grafting in the octogenarians: should we intervene, or leave them be?
title_full_unstemmed Coronary artery bypass grafting in the octogenarians: should we intervene, or leave them be?
title_short Coronary artery bypass grafting in the octogenarians: should we intervene, or leave them be?
title_sort coronary artery bypass grafting in the octogenarians: should we intervene, or leave them be?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394330/
https://www.ncbi.nlm.nih.gov/pubmed/25870618
http://dx.doi.org/10.11909/j.issn.1671-5411.2015.02.005
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