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Conformational Analysis of Misfolded Protein Aggregation by FRET and Live-Cell Imaging Techniques
Cellular homeostasis is maintained by several types of protein machinery, including molecular chaperones and proteolysis systems. Dysregulation of the proteome disrupts homeostasis in cells, tissues, and the organism as a whole, and has been hypothesized to cause neurodegenerative disorders, includi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394520/ https://www.ncbi.nlm.nih.gov/pubmed/25785563 http://dx.doi.org/10.3390/ijms16036076 |