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Favourable IFNL3 Genotypes Are Associated with Spontaneous Clearance and Are Differentially Distributed in Aboriginals in Canadian HIV-Hepatitis C Co-Infected Individuals

Canadian Aboriginals are reported to clear Hepatitis C (HCV) more frequently. We tested the association of spontaneous clearance and three single nucleotide polymorphisms (SNPs) near the Interferon-lambda 3 (IFNL3) gene (rs12979860, rs8099917, functional variant rs8103142) and compared the SNP frequ...

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Detalles Bibliográficos
Autores principales: Moqueet, Nasheed, Infante-Rivard, Claire, Platt, Robert W., Young, Jim, Cooper, Curtis, Hull, Mark, Walmsley, Sharon, Klein, Marina B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394544/
https://www.ncbi.nlm.nih.gov/pubmed/25803108
http://dx.doi.org/10.3390/ijms16036496