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The natural compound Guttiferone F sensitizes prostate cancer to starvation induced apoptosis via calcium and JNK elevation
BACKGROUND: In a cytotoxicity screen in serum-free medium, Guttiferone F showed strong growth inhibitory effect against prostate cancer cells. METHODS: Prostate cancer cells LNCaP and PC3 were treated with Guttiferone F in serum depleted medium. Sub-G1 phase distributions were estimated with flow cy...
Autores principales: | Li, Xin, Lao, Yuanzhi, Zhang, Hong, Wang, Xiaoyu, Tan, Hongsheng, Lin, Zhixiu, Xu, Hongxi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394563/ https://www.ncbi.nlm.nih.gov/pubmed/25885018 http://dx.doi.org/10.1186/s12885-015-1292-z |
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