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The natural compound Guttiferone F sensitizes prostate cancer to starvation induced apoptosis via calcium and JNK elevation

BACKGROUND: In a cytotoxicity screen in serum-free medium, Guttiferone F showed strong growth inhibitory effect against prostate cancer cells. METHODS: Prostate cancer cells LNCaP and PC3 were treated with Guttiferone F in serum depleted medium. Sub-G1 phase distributions were estimated with flow cy...

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Detalles Bibliográficos
Autores principales: Li, Xin, Lao, Yuanzhi, Zhang, Hong, Wang, Xiaoyu, Tan, Hongsheng, Lin, Zhixiu, Xu, Hongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394563/
https://www.ncbi.nlm.nih.gov/pubmed/25885018
http://dx.doi.org/10.1186/s12885-015-1292-z

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