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Levosimendan displays anti-inflammatory effects and decreases MPO bioavailability in patients with severe heart failure
Treatment of decompensated heart failure often includes administration of levosimendan. Myeloperoxidase (MPO) is released during polymorphonuclear neutrophil (PMN) degranulation, and mediates dysregulation of vascular tone in heart failure. We evaluated the effects of levosimendan-treatment on MPO i...
Autores principales: | Adam, Matti, Meyer, Sven, Knors, Henning, Klinke, Anna, Radunski, Ulf K., Rudolph, Tanja K., Rudolph, Volker, Spin, Joshua M., Tsao, Philip S., Costard-Jäckle, Angelika, Baldus, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394753/ https://www.ncbi.nlm.nih.gov/pubmed/25867530 http://dx.doi.org/10.1038/srep09704 |
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