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A Dynamic View of ATP-coupled Functioning Cycle of Hsp90 N-terminal Domain

Heat-shock protein 90 (Hsp90) is one of the most important chaperones involved in multiple cellular processes. The chaperoning function of Hsp90 is intimately coupled to the ATPase activity presented by its N-terminal domain. However, the molecular mechanism for the ATP-dependent working cycle of Hs...

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Detalles Bibliográficos
Autores principales:	Zhang, Huaqun, Zhou, Chen, Chen, Wuyan, Xu, Yechun, Shi, Yanhong, Wen, Yi, Zhang, Naixia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394755/ https://www.ncbi.nlm.nih.gov/pubmed/25867902 http://dx.doi.org/10.1038/srep09542

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