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The Mu Subunit of Plasmodium falciparum Clathrin-Associated Adaptor Protein 2 Modulates In Vitro Parasite Response to Artemisinin and Quinine
The emergence of drug-resistant parasites is a serious threat faced by malaria control programs. Understanding the genetic basis of resistance is critical to the success of treatment and intervention strategies. A novel locus associated with antimalarial resistance, ap2-mu (encoding the mu chain of...
Autores principales: | Henriques, Gisela, van Schalkwyk, Donelly A., Burrow, Rebekah, Warhurst, David C., Thompson, Eloise, Baker, David A., Fidock, David A., Hallett, Rachel, Flueck, Christian, Sutherland, Colin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394773/ https://www.ncbi.nlm.nih.gov/pubmed/25691625 http://dx.doi.org/10.1128/AAC.04067-14 |
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