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Role of ALADIN in Human Adrenocortical Cells for Oxidative Stress Response and Steroidogenesis

Triple A syndrome is caused by mutations in AAAS encoding the protein ALADIN. We investigated the role of ALADIN in the human adrenocortical cell line NCI-H295R1 by either over-expression or down-regulation of ALADIN. Our findings indicate that AAAS knock-down induces a down-regulation of genes codi...

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Detalles Bibliográficos
Autores principales:	Jühlen, Ramona, Idkowiak, Jan, Taylor, Angela E., Kind, Barbara, Arlt, Wiebke, Huebner, Angela, Koehler, Katrin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395102/ https://www.ncbi.nlm.nih.gov/pubmed/25867024 http://dx.doi.org/10.1371/journal.pone.0124582

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