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Role of Sarcoplasmic Reticulum Calcium in Development of Secondary Calcium Rise and Early Afterdepolarizations in Long QT Syndrome Rabbit Model

BACKGROUND: L-type calcium current reactivation plays an important role in development of early afterdepolarizations (EADs) and torsades de pointes (TdP). Secondary intracellular calcium (Ca(i)) rise is associated with initiation of EADs. OBJECTIVE: To test whether inhibition of sarcoplasmic reticul...

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Detalles Bibliográficos
Autores principales:	Chang, Po-Cheng, Wo, Hung-Ta, Lee, Hui-Ling, Lin, Shien-Fong, Wen, Ming-Shien, Chu, Yen, Yeh, San-Jou, Chou, Chung-Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395163/ https://www.ncbi.nlm.nih.gov/pubmed/25875599 http://dx.doi.org/10.1371/journal.pone.0123868

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