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Remission of CVB3-induced myocarditis with Astragaloside IV treatment requires A20 (TNFAIP3) up-regulation

Viral myocarditis (VMC) most prevalently caused by coxsackievirus B3 (CVB3) infection is characterized by severe cardiac inflammation. Therapeutic options for the disease are still limited. Astragaloside IV (AST-IV), a purified small molecular saponin (C(41)H(68)O(14), MW 784), is the main active co...

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Detalles Bibliográficos
Autores principales: Gui, Jun, Chen, Ruizhen, Xu, Wei, Xiong, Sidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395199/
https://www.ncbi.nlm.nih.gov/pubmed/25728713
http://dx.doi.org/10.1111/jcmm.12459

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