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Down-Regulation of MicroRNA-223 Promotes Degranulation via the PI3K/Akt Pathway by Targeting IGF-1R in Mast Cells

BACKGROUND: Mast cells play a central role in allergic and inflammatory disorders by inducing degranulation and inflammatory mediator release. Recent reports have shown that miRNAs play an important role in inflammatory response regulation. Therefore, the role of miR-223 in mast cells was investigat...

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Detalles Bibliográficos
Autores principales:	Wang, Quan, Zhao, De-Yu, Xu, Hong, Zhou, Hui, Yang, Qian-Yuan, Liu, Feng, Zhou, Guo-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395227/ https://www.ncbi.nlm.nih.gov/pubmed/25875646 http://dx.doi.org/10.1371/journal.pone.0123575

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