Cargando…

Modelling Heart Rate Kinetics

The objective of the present study was to formulate a simple and at the same time effective mathematical model of heart rate kinetics in response to movement (exercise). Based on an existing model, a system of two coupled differential equations which give the rate of change of heart rate and the rat...

Descripción completa

Detalles Bibliográficos
Autor principal: Zakynthinaki, Maria S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395265/
https://www.ncbi.nlm.nih.gov/pubmed/25876164
http://dx.doi.org/10.1371/journal.pone.0118263
_version_ 1782366407729610752
author Zakynthinaki, Maria S.
author_facet Zakynthinaki, Maria S.
author_sort Zakynthinaki, Maria S.
collection PubMed
description The objective of the present study was to formulate a simple and at the same time effective mathematical model of heart rate kinetics in response to movement (exercise). Based on an existing model, a system of two coupled differential equations which give the rate of change of heart rate and the rate of change of exercise intensity is used. The modifications introduced to the existing model are justified and discussed in detail, while models of blood lactate accumulation in respect to time and exercise intensity are also presented. The main modification is that the proposed model has now only one parameter which reflects the overall cardiovascular condition of the individual. The time elapsed after the beginning of the exercise, the intensity of the exercise, as well as blood lactate are also taken into account. Application of the model provides information regarding the individual’s cardiovascular condition and is able to detect possible changes in it, across the data recording periods. To demonstrate examples of successful numerical fit of the model, constant intensity experimental heart rate data sets of two individuals have been selected and numerical optimization was implemented. In addition, numerical simulations provided predictions for various exercise intensities and various cardiovascular condition levels. The proposed model can serve as a powerful tool for a complete means of heart rate analysis, not only in exercise physiology (for efficiently designing training sessions for healthy subjects) but also in the areas of cardiovascular health and rehabilitation (including application in population groups for which direct heart rate recordings at intense exercises are not possible or not allowed, such as elderly or pregnant women).
format Online
Article
Text
id pubmed-4395265
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-43952652015-04-21 Modelling Heart Rate Kinetics Zakynthinaki, Maria S. PLoS One Research Article The objective of the present study was to formulate a simple and at the same time effective mathematical model of heart rate kinetics in response to movement (exercise). Based on an existing model, a system of two coupled differential equations which give the rate of change of heart rate and the rate of change of exercise intensity is used. The modifications introduced to the existing model are justified and discussed in detail, while models of blood lactate accumulation in respect to time and exercise intensity are also presented. The main modification is that the proposed model has now only one parameter which reflects the overall cardiovascular condition of the individual. The time elapsed after the beginning of the exercise, the intensity of the exercise, as well as blood lactate are also taken into account. Application of the model provides information regarding the individual’s cardiovascular condition and is able to detect possible changes in it, across the data recording periods. To demonstrate examples of successful numerical fit of the model, constant intensity experimental heart rate data sets of two individuals have been selected and numerical optimization was implemented. In addition, numerical simulations provided predictions for various exercise intensities and various cardiovascular condition levels. The proposed model can serve as a powerful tool for a complete means of heart rate analysis, not only in exercise physiology (for efficiently designing training sessions for healthy subjects) but also in the areas of cardiovascular health and rehabilitation (including application in population groups for which direct heart rate recordings at intense exercises are not possible or not allowed, such as elderly or pregnant women). Public Library of Science 2015-04-13 /pmc/articles/PMC4395265/ /pubmed/25876164 http://dx.doi.org/10.1371/journal.pone.0118263 Text en © 2015 Maria S. Zakynthinaki http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Zakynthinaki, Maria S.
Modelling Heart Rate Kinetics
title Modelling Heart Rate Kinetics
title_full Modelling Heart Rate Kinetics
title_fullStr Modelling Heart Rate Kinetics
title_full_unstemmed Modelling Heart Rate Kinetics
title_short Modelling Heart Rate Kinetics
title_sort modelling heart rate kinetics
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395265/
https://www.ncbi.nlm.nih.gov/pubmed/25876164
http://dx.doi.org/10.1371/journal.pone.0118263
work_keys_str_mv AT zakynthinakimarias modellingheartratekinetics