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Elevated Atherosclerosis-Related Gene Expression, Monocyte Activation and Microparticle-Release Are Related to Increased Lipoprotein-Associated Oxidative Stress in Familial Hypercholesterolemia

OBJECTIVE: Animal and in vitro studies have suggested that hypercholesterolemia and increased oxidative stress predisposes to monocyte activation and enhanced accumulation of oxidized LDL cholesterol (oxLDL-C) through a CD36-dependent mechanism. The aim of this study was to investigate the hypothesi...

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Detalles Bibliográficos
Autores principales:	Hjuler Nielsen, Morten, Irvine, Helle, Vedel, Simon, Raungaard, Bent, Beck-Nielsen, Henning, Handberg, Aase
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395270/ https://www.ncbi.nlm.nih.gov/pubmed/25875611 http://dx.doi.org/10.1371/journal.pone.0121516

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