Parasite Load Induces Progressive Spleen Architecture Breakage and Impairs Cytokine mRNA Expression in Leishmania infantum-Naturally Infected Dogs

Canine Visceral Leishmaniasis (CVL) shares many aspects with the human disease and dogs are considered the main urban reservoir of L. infantum in zoonotic VL. Infected dogs develop progressive disease with a large clinical spectrum. A complex balance between the parasite and the genetic/immunologica...

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Detalles Bibliográficos
Autores principales: Cavalcanti, Amanda S., Ribeiro-Alves, Marcelo, Pereira, Luiza de O. R., Mestre, Gustavo Leandro, Ferreira, Anna Beatriz Robottom, Morgado, Fernanda N., Boité, Mariana C., Cupolillo, Elisa, Moraes, Milton O., Porrozzi, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395300/
https://www.ncbi.nlm.nih.gov/pubmed/25875101
http://dx.doi.org/10.1371/journal.pone.0123009

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