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Asymmetric Transcript Discovery by RNA-seq in C. elegans Blastomeres Identifies neg-1, a Gene Important for Anterior Morphogenesis

After fertilization but prior to the onset of zygotic transcription, the C. elegans zygote cleaves asymmetrically to create the anterior AB and posterior P(1) blastomeres, each of which goes on to generate distinct cell lineages. To understand how patterns of RNA inheritance and abundance arise afte...

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Detalles Bibliográficos
Autores principales: Osborne Nishimura, Erin, Zhang, Jay C., Werts, Adam D., Goldstein, Bob, Lieb, Jason D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395330/
https://www.ncbi.nlm.nih.gov/pubmed/25875092
http://dx.doi.org/10.1371/journal.pgen.1005117