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Immune Tolerance Induction Using Fetal Directed Placental Injection in Rodent Models: A Murine Model
OBJECTIVES: Induction of the immune response is a major problem in replacement therapies for inherited protein deficiencies. Tolerance created in utero can facilitate postnatal treatment. In this study, we aimed to induce immune tolerance towards a foreign protein with early gestational cell transpl...
Autores principales: | Takahashi, Kei, Endo, Masayuki, Miyoshi, Takekazu, Tsuritani, Mitsuhiro, Shimazu, Yukiko, Hosoda, Hiroshi, Saga, Kotaro, Tamai, Katsuto, Flake, Alan W., Yoshimatsu, Jun, Kimura, Tadashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395343/ https://www.ncbi.nlm.nih.gov/pubmed/25876079 http://dx.doi.org/10.1371/journal.pone.0123712 |
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