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Identification of Critical Residues of Linear B Cell Epitope on Goodpasture Autoantigen
BACKGROUND: The autoantigen of anti-glomerular basement membrane (GBM) disease has been identified as the non-collagenous domain 1 of α3 chain of type IV collagen, α3(IV)NC1. Our previous study revealed a peptide on α3(IV)NC1 as a major linear epitope for B cells and potentially nephrogenic, designa...
Autores principales: | Jia, Xiao-yu, Cui, Zhao, Li, Jian-nan, Hu, Shui-yi, Zhao, Ming-hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395375/ https://www.ncbi.nlm.nih.gov/pubmed/25874890 http://dx.doi.org/10.1371/journal.pone.0123277 |
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