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Regulatory Evolution and Voltage-Gated Ion Channel Expression in Squid Axon: Selection-Mutation Balance and Fitness Cliffs

It has been suggested that optimization of either axonal conduction velocity or the energy efficiency of action potential conduction predominates in the selection of voltage-gated sodium conductance levels in the squid axon. A population genetics model of channel gene regulatory function was used to...

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Detalles Bibliográficos
Autores principales:	Kim, Min, McKinnon, Don, MacCarthy, Thomas, Rosati, Barbara, McKinnon, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395378/ https://www.ncbi.nlm.nih.gov/pubmed/25875483 http://dx.doi.org/10.1371/journal.pone.0120785

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