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3β-Hydroxysterol Δ24-Reductase on the Surface of Hepatitis C Virus-Related Hepatocellular Carcinoma Cells Can Be a Target for Molecular Targeting Therapy
In our previous study, we demonstrated that 3β-hydroxysterol Δ24-reductase (DHCR24) was overexpressed in hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), and that its expression was induced by HCV. Using a monoclonal antibody against DHCR24 (2-152a MAb), we found that DHCR24 was speci...
Autores principales: | Saito, Makoto, Takano, Takashi, Nishimura, Tomohiro, Kohara, Michinori, Tsukiyama-Kohara, Kyoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395381/ https://www.ncbi.nlm.nih.gov/pubmed/25875901 http://dx.doi.org/10.1371/journal.pone.0124197 |
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