The Roles of Endoplasmic Reticulum Overload Response Induced by HCV and NS4B Protein in Human Hepatocyte Viability and Virus Replication

Hepatitis C virus (HCV) replication is associated with endoplasmic reticulum (ER) and its infection triggers ER stress. In response to ER stress, ER overload response (EOR) can be activated, which involves the release of Ca(2+) from ER, production of reactive oxygen species (ROS) and activation of n...

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Detalles Bibliográficos
Autores principales: Kong, Lingbao, Li, Shanshan, Huang, Mingjie, Xiong, Ying, Zhang, Qinghua, Ye, Li, Liu, Jing, Zhu, Xiangdong, Sun, Ruina, Guo, Yunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395406/
https://www.ncbi.nlm.nih.gov/pubmed/25875501
http://dx.doi.org/10.1371/journal.pone.0123190

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