Cargando…

The B Cell Adaptor Molecule Bam32 Is Critically Important for Optimal Antibody Response and Resistance to Trypanosoma congolense Infection in Mice

BACKGROUND: Bam32, a 32 kDa adaptor molecule, plays important role in B cell receptor signalling, T cell receptor signalling and antibody affinity maturation in germinal centres. Since antibodies against trypanosome variant surface glycoproteins (VSG) are critically important for control of parasite...

Descripción completa

Detalles Bibliográficos
Autores principales:	Onyilagha, Chukwunonso, Jia, Ping, Jayachandran, Nipun, Hou, Sen, Okwor, Ifeoma, Kuriakose, Shiby, Marshall, Aaron, Uzonna, Jude E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395458/ https://www.ncbi.nlm.nih.gov/pubmed/25875604 http://dx.doi.org/10.1371/journal.pntd.0003716

Ejemplares similares

Regulatory T Cells Enhance Susceptibility to Experimental Trypanosoma Congolense Infection Independent of Mouse Genetic Background
por: Okwor, Ifeoma, et al.
Publicado: (2012)

Diminazene Aceturate (Berenil) Modulates the Host Cellular and Inflammatory Responses to Trypanosoma congolense Infection
por: Kuriakose, Shiby, et al.
Publicado: (2012)

TLR-2 and MyD88-Dependent Activation of MAPK and STAT Proteins Regulates Proinflammatory Cytokine Response and Immunity to Experimental Trypanosoma congolense Infection
por: Kuriakose, Shiby, et al.
Publicado: (2019)

Thymic Stromal Lymphopoietin Is Critical for Regulation of Proinflammatory Cytokine Response and Resistance to Experimental Trypanosoma congolense Infection
por: Onyilagha, Chukwunonso, et al.
Publicado: (2017)

Crosspteryx fibrifuga leaf extract enhances host resistance to Trypanosoma congolense infection in mice by regulating host immune response and disrupting the activity of parasite superoxide dismutase enzyme
por: Ikeogu, Nnamdi, et al.
Publicado: (2023)

CD8(+) T cells Are Preferentially Activated during Primary Low Dose Leishmania major Infection but Are Completely Dispensable during Secondary Anti-Leishmania Immunity
por: Okwor, Ifeoma B., et al.
Publicado: (2014)

Molecular Regulation of Trypanosoma congolense-Induced Nitric Oxide Production in Macrophages
por: Singh, Rani, et al.
Publicado: (2013)

Host Immune Responses and Immune Evasion Strategies in African Trypanosomiasis
por: Onyilagha, Chukwunonso, et al.
Publicado: (2019)

Host Intracellular Signaling Events and Pro-inflammatory Cytokine Production in African Trypanosomiasis
por: Kuriakose, Shiby M., et al.
Publicado: (2016)

The B Lymphocyte Adaptor Molecule of 32 kD (Bam32) Regulates B Cell Antigen Receptor Signaling and Cell Survival
por: Niiro, Hiroaki, et al.
Publicado: (2002)

Protective Immunity and Vaccination Against Cutaneous Leishmaniasis
por: Okwor, Ifeoma, et al.
Publicado: (2012)

A Novel B Lymphocyte–Associated Adaptor Protein, Bam32, Regulates Antigen Receptor Signaling Downstream of Phosphatidylinositol 3-Kinase
por: Marshall, Aaron J., et al.
Publicado: (2000)

Prevalence of Trypanosoma congolense and Trypanosoma vivax in Lira District, Uganda
por: Katabazi, Aziz, et al.
Publicado: (2021)

Proteomic Selection of Immunodiagnostic Antigens for Trypanosoma congolense
por: Fleming, Jennifer R., et al.
Publicado: (2014)

Deficiency of Leishmania Phosphoglycans Influences the Magnitude but Does Not Affect the Quality of Secondary (Memory) Anti-Leishmania Immunity
por: Liu, Dong, et al.
Publicado: (2013)

Suppressive Role of Bam32/DAPP1 in Chemokine-Induced Neutrophil Recruitment
por: Hao, Li, et al.
Publicado: (2021)

Characterization of Major Surface Protease Homologues of Trypanosoma congolense
por: Marcoux, Veronica, et al.
Publicado: (2010)

Mechanisms Controlling Anaemia in Trypanosoma congolense Infected Mice
por: Noyes, Harry A., et al.
Publicado: (2009)

The life cycle of Trypanosoma (Nannomonas) congolense in the tsetse fly
por: Peacock, Lori, et al.
Publicado: (2012)

Biochemical Diversity in the Trypanosoma congolense Trans-sialidase Family
por: Gbem, Thaddeus T., et al.
Publicado: (2013)

Refractory hypoglycaemia in a dog infected with Trypanosoma congolense
por: Deschamps, Jack-Yves, et al.
Publicado: (2016)

Evidence for viable and stable triploid Trypanosoma congolense parasites
por: Tihon, Eliane, et al.
Publicado: (2017)

Genomic analysis of Isometamidium Chloride resistance in Trypanosoma congolense
por: Tihon, Eliane, et al.
Publicado: (2017)

Immune System Effects of Insulin-Like Peptide 5 in a Mouse Model
por: Vahkal, Brett, et al.
Publicado: (2021)

Differential virulence and tsetse fly transmissibility of Trypanosoma congolense and Trypanosoma brucei strains
por: Gitonga, Purity K., et al.
Publicado: (2017)

MHC Class II Restricted Innate-Like Double Negative T Cells Contribute to Optimal Primary and Secondary Immunity to Leishmania major
por: Mou, Zhirong, et al.
Publicado: (2014)

Discovery of Mating in the Major African Livestock Pathogen Trypanosoma congolense
por: Morrison, Liam J., et al.
Publicado: (2009)

Characterization of an epimastigote-stage-specific hemoglobin receptor of Trypanosoma congolense
por: Yamasaki, Shino, et al.
Publicado: (2016)

A multigene family encoding surface glycoproteins in Trypanosoma congolense
por: Thonnus, Magali, et al.
Publicado: (2017)

In vitro growth inhibition of bloodstream forms of Trypanosoma brucei and Trypanosoma congolense by iron chelators
por: Merschjohann, Karin, et al.
Publicado: (2006)

Leishmania Immunity: Advancing Immunotherapy and Vaccine Development
por: Ikeogu, Nnamdi M., et al.
Publicado: (2020)

Route of inoculation influences Trypanosoma congolense and Trypanosoma brucei brucei virulence in Swiss white mice
por: Ndungu, Kariuki, et al.
Publicado: (2019)

Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition
por: Steketee, Pieter C., et al.
Publicado: (2021)

The Activity of Red Nigerian Propolis and Some of Its Components against Trypanosoma brucei and Trypanosoma congolense
por: Alenezi, Samya S., et al.
Publicado: (2023)

Chemosensitization of Trypanosoma congolense Strains Resistant to Isometamidium Chloride by Tetracyclines and Enrofloxacin
por: Delespaux, Vincent, et al.
Publicado: (2010)

Cross-protection between Trypanosoma congolense strains of low and high virulence
por: Masumu, J., et al.
Publicado: (2009)

Complete In Vitro Life Cycle of Trypanosoma congolense: Development of Genetic Tools
por: Coustou, Virginie, et al.
Publicado: (2010)

Trypanocidal activity of ethanolic extracts of Commiphora swynnertonii Burtt on Trypanosoma congolense
por: Nagagi, Yakob P., et al.
Publicado: (2016)

Molecular characterization of tsetse’s proboscis and its response to Trypanosoma congolense infection
por: Awuoche, Erick O., et al.
Publicado: (2017)

N-glycosylation modulates enzymatic activity of Trypanosoma congolense trans-sialidase
por: Rosenau, Jana, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3tdaq3lbmmo5se59g1q133corh