Thinking big with small molecules

Synthetic chemistry has enabled scientists to explore the frontiers of cell biology, limited only by the laws of chemical bonding and reactivity. As we investigate biological questions of increasing complexity, new chemical technologies can provide systems-level views of cellular function. Here we d...

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Detalles Bibliográficos
Autores principales: Mruk, Karen, Chen, James K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395478/
https://www.ncbi.nlm.nih.gov/pubmed/25869661
http://dx.doi.org/10.1083/jcb.201501084
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author Mruk, Karen
Chen, James K.
author_facet Mruk, Karen
Chen, James K.
author_sort Mruk, Karen
collection PubMed
description Synthetic chemistry has enabled scientists to explore the frontiers of cell biology, limited only by the laws of chemical bonding and reactivity. As we investigate biological questions of increasing complexity, new chemical technologies can provide systems-level views of cellular function. Here we discuss some of the molecular probes that illustrate this shift from a “one compound, one gene” paradigm to a more integrated approach to cell biology.
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spelling pubmed-43954782015-10-13 Thinking big with small molecules Mruk, Karen Chen, James K. J Cell Biol News Synthetic chemistry has enabled scientists to explore the frontiers of cell biology, limited only by the laws of chemical bonding and reactivity. As we investigate biological questions of increasing complexity, new chemical technologies can provide systems-level views of cellular function. Here we discuss some of the molecular probes that illustrate this shift from a “one compound, one gene” paradigm to a more integrated approach to cell biology. The Rockefeller University Press 2015-04-13 /pmc/articles/PMC4395478/ /pubmed/25869661 http://dx.doi.org/10.1083/jcb.201501084 Text en © 2015 Mruk and Chen This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle News
Mruk, Karen
Chen, James K.
Thinking big with small molecules
title Thinking big with small molecules
title_full Thinking big with small molecules
title_fullStr Thinking big with small molecules
title_full_unstemmed Thinking big with small molecules
title_short Thinking big with small molecules
title_sort thinking big with small molecules
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395478/
https://www.ncbi.nlm.nih.gov/pubmed/25869661
http://dx.doi.org/10.1083/jcb.201501084
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