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A small part of myosin IIB takes on a big role in cell polarity
A migrating cell must establish front-to-back polarity in order to move. In this issue, Juanes-Garcia et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201407059) report that a short serine-rich motif in nonmuscle myosin IIB is required to establish the cell’s rear. This motif represents a n...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395479/ https://www.ncbi.nlm.nih.gov/pubmed/25869662 http://dx.doi.org/10.1083/jcb.201503079 |
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author | Fenix, Aidan M. Burnette, Dylan T. |
author_facet | Fenix, Aidan M. Burnette, Dylan T. |
author_sort | Fenix, Aidan M. |
collection | PubMed |
description | A migrating cell must establish front-to-back polarity in order to move. In this issue, Juanes-Garcia et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201407059) report that a short serine-rich motif in nonmuscle myosin IIB is required to establish the cell’s rear. This motif represents a new paradigm for what determines directional cell migration. |
format | Online Article Text |
id | pubmed-4395479 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-43954792015-10-13 A small part of myosin IIB takes on a big role in cell polarity Fenix, Aidan M. Burnette, Dylan T. J Cell Biol Reviews A migrating cell must establish front-to-back polarity in order to move. In this issue, Juanes-Garcia et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201407059) report that a short serine-rich motif in nonmuscle myosin IIB is required to establish the cell’s rear. This motif represents a new paradigm for what determines directional cell migration. The Rockefeller University Press 2015-04-13 /pmc/articles/PMC4395479/ /pubmed/25869662 http://dx.doi.org/10.1083/jcb.201503079 Text en © 2015 Fenix and Burnette This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/). |
spellingShingle | Reviews Fenix, Aidan M. Burnette, Dylan T. A small part of myosin IIB takes on a big role in cell polarity |
title | A small part of myosin IIB takes on a big role in cell polarity |
title_full | A small part of myosin IIB takes on a big role in cell polarity |
title_fullStr | A small part of myosin IIB takes on a big role in cell polarity |
title_full_unstemmed | A small part of myosin IIB takes on a big role in cell polarity |
title_short | A small part of myosin IIB takes on a big role in cell polarity |
title_sort | small part of myosin iib takes on a big role in cell polarity |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395479/ https://www.ncbi.nlm.nih.gov/pubmed/25869662 http://dx.doi.org/10.1083/jcb.201503079 |
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