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Excision of translesion synthesis errors orchestrates responses to helix-distorting DNA lesions

In addition to correcting mispaired nucleotides, DNA mismatch repair (MMR) proteins have been implicated in mutagenic, cell cycle, and apoptotic responses to agents that induce structurally aberrant nucleotide lesions. Here, we investigated the mechanistic basis for these responses by exposing cell...

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Detalles Bibliográficos
Autores principales: Tsaalbi-Shtylik, Anastasia, Ferrás, Cristina, Pauw, Bea, Hendriks, Giel, Temviriyanukul, Piya, Carlée, Leone, Calléja, Fabienne, van Hees, Sandrine, Akagi, Jun-Ichi, Iwai, Shigenori, Hanaoka, Fumio, Jansen, Jacob G., de Wind, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395481/
https://www.ncbi.nlm.nih.gov/pubmed/25869665
http://dx.doi.org/10.1083/jcb.201408017

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