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Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling

It is well established that the spatial- and temporal-restricted generation and turnover of phosphoinositides (PIs) by a cascade of PI-metabolizing enzymes is a key regulatory mechanism in the endocytic pathway. Here, we demonstrate that the Sac1 domain–containing protein Sac2 is a PI 4-phosphatase...

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Detalles Bibliográficos
Autores principales: Hsu, FoSheng, Hu, Fenghua, Mao, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395482/
https://www.ncbi.nlm.nih.gov/pubmed/25869669
http://dx.doi.org/10.1083/jcb.201408027