The Clinical Relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 Network in Chemoresistant Non-small-cell Lung Cancer

Programmed cell death ligand-1 (PD-L1) has recently gained considerable attention for its role in tumor immune escape. Here, we identify a miR-197/CKS1B/STAT3-mediated PD-L1 network in chemoresistant non-small-cell lung cancer (NSCLC), independent of immunoinhibitory signals. miR-197 is downregulate...

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Detalles Bibliográficos
Autores principales: Fujita, Yu, Yagishita, Shigehiro, Hagiwara, Keitaro, Yoshioka, Yusuke, Kosaka, Nobuyoshi, Takeshita, Fumitaka, Fujiwara, Tomohiro, Tsuta, Koji, Nokihara, Hiroshi, Tamura, Tomohide, Asamura, Hisao, Kawaishi, Makoto, Kuwano, Kazuyoshi, Ochiya, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395779/
https://www.ncbi.nlm.nih.gov/pubmed/25597412
http://dx.doi.org/10.1038/mt.2015.10

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