Genetic variation at the human connexin 43 locus but not at the connexin 40 locus is associated with left bundle branch block

BACKGROUND: Bundle branch block (BBB) has been regarded as a disease of the conduction system, but occurs in mice lacking connexin 40 (expressed in atria, proximal conduction system) or connexin 43 (expressed in Purkinje cells, cardiomyocytes). OBJECTIVE: The aim of this paper is to explore whether...

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Detalles Bibliográficos
Autores principales: Ladenvall, Per, Andersson, Björn, Dellborg, Mikael, Hansson, Per-Olof, Eriksson, Henry, Thelle, Dag, Eriksson, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395834/
https://www.ncbi.nlm.nih.gov/pubmed/25893100
http://dx.doi.org/10.1136/openhrt-2014-000187

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