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FBN-1, a fibrillin-related protein, is required for resistance of the epidermis to mechanical deformation during C. elegans embryogenesis

During development, biomechanical forces contour the body and provide shape to internal organs. Using genetic and molecular approaches in combination with a FRET-based tension sensor, we characterized a pulling force exerted by the elongating pharynx (foregut) on the anterior epidermis during C. ele...

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Detalles Bibliográficos
Autores principales: Kelley, Melissa, Yochem, John, Krieg, Michael, Calixto, Andrea, Heiman, Maxwell G, Kuzmanov, Aleksandra, Meli, Vijaykumar, Chalfie, Martin, Goodman, Miriam B, Shaham, Shai, Frand, Alison, Fay, David S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395870/
https://www.ncbi.nlm.nih.gov/pubmed/25798732
http://dx.doi.org/10.7554/eLife.06565