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Response to Nodal morphogen gradient is determined by the kinetics of target gene induction

Morphogen gradients expose cells to different signal concentrations and induce target genes with different ranges of expression. To determine how the Nodal morphogen gradient induces distinct gene expression patterns during zebrafish embryogenesis, we measured the activation dynamics of the signal t...

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Detalles Bibliográficos
Autores principales: Dubrulle, Julien, Jordan, Benjamin M, Akhmetova, Laila, Farrell, Jeffrey A, Kim, Seok-Hyung, Solnica-Krezel, Lilianna, Schier, Alexander F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395910/
https://www.ncbi.nlm.nih.gov/pubmed/25869585
http://dx.doi.org/10.7554/eLife.05042