Cargando…

Response to Nodal morphogen gradient is determined by the kinetics of target gene induction

Morphogen gradients expose cells to different signal concentrations and induce target genes with different ranges of expression. To determine how the Nodal morphogen gradient induces distinct gene expression patterns during zebrafish embryogenesis, we measured the activation dynamics of the signal t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dubrulle, Julien, Jordan, Benjamin M, Akhmetova, Laila, Farrell, Jeffrey A, Kim, Seok-Hyung, Solnica-Krezel, Lilianna, Schier, Alexander F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Developmental Biology and Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395910/ https://www.ncbi.nlm.nih.gov/pubmed/25869585 http://dx.doi.org/10.7554/eLife.05042

Ejemplares similares

Extracellular interactions and ligand degradation shape the nodal morphogen gradient
por: Wang, Yin, et al.
Publicado: (2016)

Nodal and planar cell polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements
por: Williams, Margot LK, et al.
Publicado: (2020)

Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm
por: Montague, Tessa G, et al.
Publicado: (2017)

Decoding temporal interpretation of the morphogen Bicoid in the early Drosophila embryo
por: Huang, Anqi, et al.
Publicado: (2017)

Nodal patterning without Lefty inhibitory feedback is functional but fragile
por: Rogers, Katherine W, et al.
Publicado: (2017)

Bone morphogenic protein signalling suppresses differentiation of pluripotent cells by maintaining expression of E-Cadherin
por: Malaguti, Mattias, et al.
Publicado: (2013)

Spatio-temporal regulation of concurrent developmental processes by generic signaling downstream of chemokine receptors
por: Malhotra, Divyanshu, et al.
Publicado: (2018)

An essential role for maternal control of Nodal signaling
por: Kumari, Pooja, et al.
Publicado: (2013)

The Apelin receptor enhances Nodal/TGFβ signaling to ensure proper cardiac development
por: Deshwar, Ashish R, et al.
Publicado: (2016)

Derivation of trophoblast stem cells from naïve human pluripotent stem cells
por: Dong, Chen, et al.
Publicado: (2020)

Functional evolution of a morphogenetic gradient
por: Kwan, Chun Wai, et al.
Publicado: (2016)

Concentration dependent chromatin states induced by the bicoid morphogen gradient
por: Hannon, Colleen E, et al.
Publicado: (2017)

Maternal Factors and Nodal Autoregulation Orchestrate Nodal Gene Expression for Embryonic Mesendoderm Induction in the Zebrafish
por: Xing, Cencan, et al.
Publicado: (2022)

The pattern of nodal morphogen signaling is shaped by co-receptor expression
por: Lord, Nathan D, et al.
Publicado: (2021)

Bicoid gradient formation and function in the Drosophila pre-syncytial blastoderm
por: Ali-Murthy, Zehra, et al.
Publicado: (2016)

Correction: Bicoid gradient formation and function in the Drosophila pre-syncytial blastoderm
por: Ali-Murthy, Zehra, et al.
Publicado: (2017)

Combinatorial Signals of Activin/Nodal and Bone Morphogenic Protein Regulate the Early Lineage Segregation of Human Embryonic Stem Cells
por: Wu, Zhao, et al.
Publicado: (2008)

Cellular interpretation of the long-range gradient of Four-jointed activity in the Drosophila wing
por: Hale, Rosalind, et al.
Publicado: (2015)

To B (Bone Morphogenic Protein-2) or Not to B (Bone Morphogenic Protein-2): Mesenchymal Stem Cells May Explain the Protein’s Role in Osteosarcomagenesis
por: Xu, Chunfeng, et al.
Publicado: (2021)

Wnt, Ptk7, and FGFRL expression gradients control trunk positional identity in planarian regeneration
por: Lander, Rachel, et al.
Publicado: (2016)

Frazzled promotes growth cone attachment at the source of a Netrin gradient in the Drosophila visual system
por: Akin, Orkun, et al.
Publicado: (2016)

Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin
por: Kim, Seok-Hyung, et al.
Publicado: (2011)

Live cell-lineage tracing and machine learning reveal patterns of organ regeneration
por: Viader-Llargués, Oriol, et al.
Publicado: (2018)

Feedback regulation of cytoneme-mediated transport shapes a tissue-specific FGF morphogen gradient
por: Du, Lijuan, et al.
Publicado: (2018)

Photoreceptors generate neuronal diversity in their target field through a Hedgehog morphogen gradient in Drosophila
por: Bostock, Matthew P, et al.
Publicado: (2022)

Collagen type I promotes osteogenic differentiation of amniotic membrane-derived mesenchymal stromal cells in basal and induction media
por: Akhir, Haselamirrah Mohd, et al.
Publicado: (2020)

Robustness of the Dorsal morphogen gradient with respect to morphogen dosage
por: Al Asafen, Hadel, et al.
Publicado: (2020)

Editorial: Morphogenic Cascades Underlying Regeneration and Plasticity After Nervous System Injury
por: Lutz, David, et al.
Publicado: (2021)

Ngn1 inhibits astrogliogenesis through induction of miR-9 during neuronal fate specification
por: Zhao, Jing, et al.
Publicado: (2015)

High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures
por: Minn, Kyaw Thu, et al.
Publicado: (2020)

Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation
por: Liu, Yinzi, et al.
Publicado: (2017)

Cost-precision trade-off relation determines the optimal morphogen gradient for accurate biological pattern formation
por: Song, Yonghyun, et al.
Publicado: (2021)

C-Terminal Peptide Modifications Reveal Direct and Indirect Roles of Hedgehog Morphogen Cholesteroylation
por: Manikowski, Dominique, et al.
Publicado: (2021)

Gradients of glucose metabolism regulate morphogen signalling required for specifying tonotopic organisation in the chicken cochlea
por: O'Sullivan, James DB, et al.
Publicado: (2023)

Patterning principles of morphogen gradients
por: Simsek, M. Fethullah, et al.
Publicado: (2022)

Aging induces aberrant state transition kinetics in murine muscle stem cells
por: Kimmel, Jacob C., et al.
Publicado: (2020)

Timing Does Matter: Nerve-Mediated HDAC1 Paces the Temporal Expression of Morphogenic Genes During Axolotl Limb Regeneration
por: Wang, Mu-Hui, et al.
Publicado: (2021)

Glycogen Synthase Kinase 3β and Activin/Nodal Inhibition in Human Embryonic Stem Cells Induces a Pre-Neuroepithelial State That Is Required for Specification to a Floor Plate Cell Lineage
por: Denham, Mark, et al.
Publicado: (2012)

Low oxygen levels induce the expression of the embryonic morphogen Nodal
por: Quail, Daniela F., et al.
Publicado: (2011)

Embryonic Morphogen Nodal Promotes Breast Cancer Growth and Progression
por: Quail, Daniela F., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_5qtsgtqf866tqd99jig2kbh9ch