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Management of dual intracranial germinoma by radiotherapy alone

Synchronous intracranial germ cell tumor in the pineal and suprasellar region is rare. They represent only 5–10% of all intracranial germinomas. They are also known by the entity “double midline atypical teratoma” and are common in the second decade of life. We report a case of an 11-year-old girl h...

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Detalles Bibliográficos
Autores principales: Gupta, Rakesh, Songara, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395943/
https://www.ncbi.nlm.nih.gov/pubmed/25878742
http://dx.doi.org/10.4103/1817-1745.154330
Descripción
Sumario:Synchronous intracranial germ cell tumor in the pineal and suprasellar region is rare. They represent only 5–10% of all intracranial germinomas. They are also known by the entity “double midline atypical teratoma” and are common in the second decade of life. We report a case of an 11-year-old girl having dual midline intracranial lesions with obstructive hydrocephalus treated by ventriculo-peritoneal shunt. Diagnosis of germinoma was made on the basis of imaging and elevated beta-human chorionic gonadotropin in cerebrospinal fluid. Radiotherapy was instituted, which resulted in the total disappearance of both the lesions. Clinical expression, diagnosis and management strategies are discussed.