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Efficient representation of uncertainty in multiple sequence alignments using directed acyclic graphs

BACKGROUND: A standard procedure in many areas of bioinformatics is to use a single multiple sequence alignment (MSA) as the basis for various types of analysis. However, downstream results may be highly sensitive to the alignment used, and neglecting the uncertainty in the alignment can lead to sig...

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Detalles Bibliográficos
Autores principales:	Herman, Joseph L, Novák, Ádám, Lyngsø, Rune, Szabó, Adrienn, Miklós, István, Hein, Jotun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395974/ https://www.ncbi.nlm.nih.gov/pubmed/25888064 http://dx.doi.org/10.1186/s12859-015-0516-1

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