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Glutamate receptors function as scaffolds for the regulation of β-amyloid and cellular prion protein signaling complexes

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that affects 36 million people worldwide, but currently has no effective treatment options. One of the original hallmarks of AD are plaques comprised of beta amyloid (Aβ) and neurofibrillary tangles comprised of phosphorylated Tau...

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Detalles Bibliográficos
Autores principales: Hamilton, Alison, Zamponi, Gerald W, Ferguson, Stephen S G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395978/
https://www.ncbi.nlm.nih.gov/pubmed/25888324
http://dx.doi.org/10.1186/s13041-015-0107-0